Manufacturing Advisory Committee (MAC)

Adaptimmune, a leader in T-cell therapy, is a multinational, clinical-stage biopharmaceutical company focused on developing novel immunotherapies using its proprietary SPEAR T-cell receptor platform to treat solid tumors, which has the potential to transform the treatment of cancer.

Our proprietary SPEAR T-cell platform has generated a strong pipeline of affinity-enhanced T-cell therapies, with multiple INDs open. We use these therapies to harness the body's own immune system to find and destroy diseased cells. Our SPEAR TCR therapies offer promise to patients that often have no other options. We are working hard to make that promise a reality.

The Advanced Centre for Biochemical Engineeering hosts the MBI® Modular Training Programme for the Bioindustries.

Allergan Biologics Ltd. (an affiliate of Allergan plc.) is a state of the art development and clinical manufacturing facility and is a Centre of Excellence for Biologics development.

AstraZeneca is a major contributor to UK science and innovation investment, economic prosperity and to patient health. The UK is home to the organisations global headquarters and major research and development and manufacturing facilities. AstraZeneca invest over £1.3 billion per year in research and development in the UK.

Asymptote specialises in cryopreservation and liquid nitrogen-free freezers developed for GMP compliant cold chains for regenerative medicine and biobanking

Avacta’s therapeutics division, based in Cambridge, U.K. develops novel cancer immunotherapies combining its two proprietary platforms – Affimer® biotherapeutics and pre|CISIONTM tumour targeted chemotherapy. With this approach, the Company aims to address the lack of a durable response to current immunotherapies experienced by most patients.

BTG is a global healthcare company focused on Interventional Medicine. Our innovative medical technology helps physicians treat their patients through minimally invasive procedures.

The Cell and Gene Therapy Catapult was established in 2012 as an independent centre of excellence to advance the growth of the UK cell and gene therapy industry, by bridging the gap between scientific research and full-scale commercialisation.

Instil Bio (UK) Limited is focused on “Personalised cellular medicine” using the patient’s own immune system to be harnessed in order to fight disease.

The Centre for Process Innovation is a UK-based technology innovation centre and part of the High Value Manufacturing Catapult.

The Clinical BioManufacturing Facility is the University of Oxford’s GMP (Good Manufacturing Practice) manufacturing facility.

Cobra provides a comprehensive biopharmaceuticals service offering, with multi-functional project teams nurturing products from pre-clinical to commercial scale GMP manufacture.

Envigo is one of the world's largest Contract Research Organisations.

eXmoor pharma is a technical and strategic consultancy in biopharmaceuticals, secondary pharmaceuticals and cell & gene therapies. We work in capital projects and GMP biomanufacturing.

Freeline is a leading clinical-stage biotechnology company. We focus on development and commercialisation of innovative gene therapies to change lives.

FUJIFILM Diosynth Biotechnologies is an industry-leading Biologics Contract Manufacturing Organisation with locations in Billingham, UK and Research Triangle Park, North Carolina, USA.

GE is a global infrastructure, finance and media company taking on the world's toughest challenges.

GSK is a global pharmaceutical company dedicated to helping people feel better, do more and live longer.

Horizon is a revenue-generating life science group supplying research tools to organizations engaged in translational genomics research and the development of personalized medicines.

Innovate UK is part of UK Research and Innovation, a non-departmental public body funded by a grant-in-aid from the UK government.

Ipsen is a global specialty-driven pharmaceutical company with total sales exceeding €1.1 billion in 2010

As a worldwide leader supplying the pharmaceutical and biotechnology industries with biopharmaceuticals, Lonza furnishes seven different markets with state-of-the-art products, services, and research.

The Clinical Translation Partnerships (CTP) was established in 2010 to support scientists bringing new cellular therapies into clinical practice.

Nightstar is a private biopharmaceutical company, funded by Syncona LLP, an independent subsidiary of the Wellcome Trust, focused on the development of therapies for retinal dystrophies.

Oxford BioMedica plc (LSE: OXB) is a biopharmaceutical company developing innovative gene-based medicines and therapeutic vaccines that aim to improve the lives of patients with high unmet medical needs.

Pall Corporation (NYSE:PLL) is a global leader in the high-tech filtration, separation and purification industry. We’ve become an industry leader by helping a diverse range of customers solve complex fluid management challenges.

Puridify offers purification solutions for biotherapeutic manufacturing. Our flagship product, FibroSelect, reduces biotherapeutic manufacturing costs by c.25%.

Purolite is the only globally-acting company that focuses exclusively on advanced resin technologies and has been producing resins for over 35 years.

ReNeuron are a leading, clinical-stage stem cell business. Our primary objective is the development of novel stem cell therapies targeting areas of significant unmet or poorly met medical need.

Roslin Cells are world leaders in the isolation of new clinical grade pluripotent stem cells for use in research and therapy.

As one of the world’s largest influenza vaccine providers, Seqirus is a major contributor to the prevention of influenza globally and a transcontinental partner in pandemic preparedness.

TAP Biosystems (TAP) is an innovative UK company providing automation systems and services to improve productivity in life science research, development and production.

TAP design, develop and support advanced cell culture and processing systems with applications in regenerative medicine, bioprocess development, biologics production and drug discovery. We also provide custom automation solutions for cell therapies, bioprocessing and sample management.

Recent innovations include a novel microscale bioreactor and a collagen-based 3D tissue modelling system.

TCR2 is a clinical-stage immunotherapy company developing a new generation of T cell therapies for patients suffering from cancer.

Thermo Fisher Scientific is the world leader in serving science, with revenues of more than $20 billion and approximately 70,000 employees globally. Our mission is to enable our customers to make the world healthier, cleaner and safer. We help our customers accelerate life sciences research, solve complex analytical challenges, improve patient diagnostics, deliver medicines to market and increase laboratory productivity. Through our premier brands – Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific and Unity Lab Services – we offer an unmatched combination of innovative technologies, purchasing convenience and comprehensive services.