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SUMMARY:Programming Cytokine Sensing: A Blueprint for Durable CAR-T
DESCRIPTION:Interferon-gamma (IFNγ) is a double-edged cytokine for adoptive cell therapy in solid tumors. While IFNγ is required for CAR-T cell efficacy against these cancers, its direct uptake by CAR-T cells with a CD28 costimulatory domain can restrict their expansion, persistence, and overall effectiveness. To address this challenge, new strategies are being developed to re-engineer CAR-T cells, allowing them to overcome their limitations and produce more durable antitumor responses.\n
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 Event details: https://www.bioindustry.org/events/our-events/programming-cytokine-sensing-a-blueprint-for-durable-car-t-1.html
PRIORITY:1
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