Adaptive Manufacturing Webinar

Adaptive manufacturing? Conceptually this envisages a system in which the parts of a process – for us the manufacture of a successful product – can be integrated with the incorporation of greater automation, in which control processes respond to real-time measurement information about process events. Again, in concept, this should allow continuous adaptation and control to maximise the predictability of achieving product quality and consistency. That’s the theory but what is the reality for the bioprocessing sector? Are we able to learn the lessons from other sectors and develop the innovative automated solutions required? This will be the focus of the webinar. We do not know if we have answers but we hope that the presentations will reflect current thinking and stimulate further sector-wide discussions.

 

Professor Alan Dickson

Professor of Biotechnology

University of Manchester

Alan Dickson is Professor of Biotechnology at the University of Manchester with BSc and PhD from The University of Edinburgh. Alan is a molecular cellular biologist and works with industrial partners to enhance expression and manufacture of recombinant proteins in bioprocessing. Current grant funding includes Research Council and industrially funded projects. He was a member of the Steering Group of the BBSRC Bioprocessing Research Industry Club (BRIC) and is a member of the Executive Committee of the European Society for Animal Cell Technology (ESACT). He leads the multi-disciplinary Centre of Excellence in Biopharmaceuticals (COEBP) based in the Manchester Institute of Biotechnology. The COEBP links researchers from biological, chemical, chemical engineering medical and physical sciences backgrounds to applying novel approaches to challenges of manufacture of biologics, promoting industrial-academic linkages and providing access to research technologies including high-throughput and high-content cell culture robotics. Alan is Co-Director of BioProNET, a BBSRC NIBB, co-sponsored by EPSRC,that promotes industrial-academic interactions.

Dr Damian Marshall

Head of Analytical Development

Cell and Gene Therapy Catapult

Damian Marshall is the head of analytical development for the Cell and Gene Therapy Catapult. He has almost 20 years’ of industrial experience focussed on the development of cell therapies and the integration of new technologies for product characterisation. His team works closely with a wide range of therapy developers, implementing analytical approaches to support the clinical and commercial development of their products and addressing some of the fundamental challenges faced by the cell and gene therapy field.

Andy Topping

Chief Scientific Officer

Fujifilm Diosynth Biotechnologies

Andy has worked in the biopharmaceutical industry for more than 25 years. Originally trained as a molecular biologist with a Ph.D. from the University of Wales in Cardiff he has led development and manufacturing projects bringing over 50 proteins from microbial and mammalian expression systems into the clinic. He is Chief Scientific Officer for the CDMO Fujifilm Diosynth Biotechnologies, responsible for science and innovation across the company’s sites in the UK and US.


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