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Translational Biomarkers, Project Manager

F-Star Therapeutics

Cambridge, UK

The Translational Science team is growing to meet the exciting challenges of pre-clinical and clinical big data initiatives at F-star, including DNA and RNA expression, digital spatial profiling and proteomics. 

We are now seeking a creative, proactive and highly motivated Computational Biologist/Bioinformatician/Data Scientist with strong expertise in cancer genomics and/or immuno-oncology to join the team.

The role, which is fully integrated in the Translation Sciences group, will involve working across multiple teams and projects to deliver actionable insights from clinical and pre-clinical data and developing F-star’s bioinformatics capabilities to discover new biomarkers. You will generate novel hypothesis and develop our biomarker plans through the design of experiments and the analysis of in-house generated and publicly available multi-omics clinical pharmacology datasets. 


  • Work within and across teams to understand various scientific and technical challenges and proactively impact these using bioinformatics. 
  • Apply appropriate analytical approaches to deliver actionable insights driving patient selection, biomarker discovery and development of the next generation of cancer therapeutics.
  • Integrate publicly and in-house generated dataset to produce multiparametric analysis from different biomarker platforms.
  • Provide innovative ways to identify and visualise meaningful patterns in complex data. 
  • Develop methods for omics-based characterization of drug response.
  • Work within and across multidisciplinary teams/projects to translate findings into clinically applicable biomarkers for patient response and stratification.
  • Provide guidance on experimental design and work collaboratively to influence generation of data assets.  Share code and train peers in the tools critical to understanding complex data. 
  • Collaborate with industry partners and academia. 
  • Publish your work in high impact journals.