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Senior Research Scientist

Vertex Pharmaceuticals

Oxford, UK

Our Human Disease Modelling group is seeking an innovative and dynamic Senior Research Scientist to play a pivotal role in expanding our capabilities in disease-relevant human cell models at the Oxford Research site. Successful candidates would help us utilize a range of technologies to build such models that can be leveraged to test therapeutic hypotheses, discover novel target biology, characterize potential drug candidates and develop translational biomarkers. This position will involve working in close collaboration with other researchers and across drug discovery disciplines to ensure that we deliver medicines that treat the underlying cause of serious diseases and provide transformative benefit for our patients.

Key responsibilities

  • Independently design and (where appropriate) execute and elaborate technically challenging experiments using disease-relevant cell-based models to test therapeutic hypotheses
  • Champion and leverage cutting edge molecular cell biology techniques and technologies for in vitro disease modeling
  • Effectively distil complex, multi-dimensional data and results into concise concepts and clearly propose strategic and experimental actions 
  • Proactively communicate and work highly effectively within and between teams
  • Collaborate extensively and work on shared projects with other scientific colleagues and cross-functional teams, including others in the Biology Department and beyond