FIRST PATIENT DOSING IN PHASE I CLINICAL TRIAL OF ULTRA-RAPID ACTING INSULIN PRODUCT CANDIDATE AT247 FOR DIABETES

Cambridge, UK., 7th May 2019: Arecor Limited (“Arecor” or “the Company”), the specialty pharmaceutical company leveraging its innovative and proprietary formulation technology to develop superior treatments for a range of disease areas, including diabetes, today announces dosing of the first patient in its Phase I clinical trial for its ultra-rapid acting insulin product candidate, AT247.


Arecor’s AT247 is an ultra-rapid acting prandial insulin product candidate targeting improved treatment for people living with Type I diabetes. The novel formulation of AT247 is designed to deliver an acceleration of insulin absorption, post injection, to enable more effective management of blood glucose levels. This is to ensure lower variability of post-meal blood glucose elevations and the potential clinical benefits of avoiding both hypo and hyperglycaemia.


The double-blind, randomised, three-way cross over Phase I clinical study will compare the pharmacokinetic and pharmacodynamic profiles of AT247 to current best in class insulin treatments. The trial is being conducted in Austria at an internationally recognised centre of excellence in the field of diabetes research and preliminary results are expected towards the end of the year.


Sarah Howell, Chief Executive Officer at Arecor, said: "The initiation of the AT247 Phase I clinical trial is an important step in our strategy to develop even faster acting insulins targeted at improving treatment and healthcare outcomes for people living with Type I diabetes. I look forward to reporting on the progress of this product candidate, the first in our proprietary product development pipeline.”


-ENDS-

 

For more information, please contact:
Arecor Limited | www.arecor.com
Dr Sarah Howell, Chief Executive Officer | Tel: +44 (0) 1223 426060 | Email: sarah.howell@arecor.com
Susan Lowther, Chief Financial Officer | Tel: +44 (0) 1223 426060 | Email: susan.lowther@arecor.com
PeckwaterPR | www.peckwaterpr.co.uk
Tarquin Edwards | Mob : +44 (0) 7879 458 364 | Email : tarquin.edwards@peckwaterpr.co.uk

 

Note to Editors
About Arecor (www.arecor.com)
Arecor Limited is a leader in developing superior biopharmaceuticals through the application of an innovative formulation technology platform. Arecor is leveraging this platform to develop a portfolio of proprietary products that will enable improved treatments for diabetes via the innovative reformulation of approved proteins and peptides. Arecor's product portfolio also includes:

  • Novel insulin formulations to deliver ultra-rapid acting insulin analogs and;
  • Ultra-concentrated rapid acting insulin to enable the miniaturisation of devices,
  • Stable aqueous glucagon for emergency and artificial pancreas use, and
  • A series of undisclosed pre-clinical programmes.

Arecor partners with leading pharmaceutical and biotech companies to deliver superior reformulations of their proprietary products, which would otherwise not be possible using conventional formulation science.