• Pre Clinical And Clinical Research

Arcinova announces major investment in Alnwick site with the installation of the R1000 capsule fill machine from 3P Innovation

Arcinova, a multi-service Contract Development and Manufacturing Organisation (CDMO) based in Alnwick, Northumberland, has recently taken delivery and commissioned the award winning R1000 Robotic Capsule Filler from life-sciences automation company 3P innovation, as part of the ‘Fill-Inova’ project.

Iksuda Therapeutics enters license agreement with University of Goettingen to develop a new generation of antibody drug conjugates

• Iksuda licenses novel protein-alkylating, tumour-activated pro-drug payload series to develop ADCs with enhanced therapeutic index • Development to focus on targets associated with haematological and solid tumours

Synthetic Biology start up NanoSyrinx secures capital to develop its fully customisable platform for intra-cellular engineering

NanoSyrinx is the first company to engineer ‘nanosyringes’, a selective non-viral peptide and protein delivery system identified in an undisclosed organism. The company will focus on direct cytosolic delivery of genome editing enzymes and therapeutic proteins in vivo, with key applications in the cell and gene therapy space.

CTI Clinical Trial and Consulting Services Announce Dosing of First Subject in Janssen’s ENSEMBLE Phase 3 COVID-19 Vaccine Trial

CTI research site is the lead enroller of the study, with dozens of patients randomized in the first week, and more scheduled for dosing in the next several.

Enesi Pharma Appoints Vaccine Development Expert Dr Keith Howard as CSO to Lead ImplaVax® Development

Enesi Pharma is delighted to announce the appointment of Dr Keith Howard as Chief Scientific Officer. Dr Howard is a seasoned vaccine development expert who will lead Enesi’s R&D efforts to develop novel solid-dose vaccines for needle-free delivery for both in-house and partnered programmes, progressing them into clinical development.

Accelerate@Babraham Start-up Programme underway with four new life science start-ups taking part in the five month programme

Benefits of the programme include access to the Babraham Research Campus bio-incubator facilities, an extended programme of mentoring and support and £10k undiluted funding

CTI Clinical Trial and Consulting Services Announces Acquisition of Middle East/Northern African based Clinart

CTI announces the acquisition of Clinart, a full-service contract research organization with strong local expertise in the Middle East and Northern Africa (MENA) region.

CombiGene and CGT Catapult collaboration completes development of quality control analytical assays for clinical production of CombiGene’s AAV-based gene therapy for the treatment of epilepsy

The extensive and advanced work to develop the critical analytical assays needed for quality control in the manufacture of the AAV1 based gene therapy product CG01 has now been completed in a collaboration between CombiGene and CGT Catapult. CombiGene will now integrate the analytical assays into its production process, taking it another step closer to its final large scale production design for clinical trials and commercial distribution.

Advanced Therapy Treatment Centre network awarded £9.5m further investment

The UK Government grant will support new and existing projects until March 2022. Funding will ensure that the positive impact of the ATTC network continues; further optimising the UK ecosystem for routine adoption of advanced therapies.

Evonetix and Analog Devices Collaborate on Third-Generation DNA Synthesis Platform

EVONETIX LTD (‘Evonetix’), the synthetic biology company developing a desktop platform for scalable, high-fidelity and rapid gene synthesis, today announced a collaboration with leading, global high-performance analog technology company, Analog Devices, Inc. The companies will work together on the advancement and commercial scale-up of Evonetix’s proprietary microelectromechanical systems (MEMS)-based silicon chips and accelerate the development of Evonetix’s first product, a DNA desktop writer.