Research Associate in Molecular Dynamics (10376)
Rosalind Franklin Institute
The Rosalind Franklin Institute (the Franklin) is a technology institute for life science, creating innovative technologies that transform our understanding of life. Our technologies, borne out of innovation in physical sciences, create collaborations and new avenues in life science which will lead to new therapeutics and advance our understanding of human biology.
We are seeking a highly motivated and experienced biophysicist/computational chemist to join our liquid phase electron microscopy team to develop molecular dynamics simulations of cryo-EM and LPEM maps to inform our experimental observations, as part of our Science Challenge on multi-dimensional imaging. Our aim is to develop simulated “movies” of the protein conformational ensemble from time-resolved cryo-EM datasets and use these to better understand the maps produced in liquid phase EM applications. Experience working with computational approaches to protein dynamics is essential, expertise in the application of molecular dynamics to cryo-EM, LPEM or other structural biology methods (X-ray/NMR/Light microscopy etc.) desirable.
As a Research Associate at the Franklin, you will apply your scientific knowledge and skills to our goal of understanding protein dynamics in liquid phase electron microscopy, bringing independent, creative science to our project team. Through this work, you will build scientific independence, develop new science and leadership skills, and establish a growing reputation externally.