ImmuONE Ltd

ImmuONE is a CRO biotechnology company that specialises in human alveolar macrophage responses, epithelial cell culture platforms and testing services.

ImmuONE provides innovative respiratory in vitro cell culture products and contract research services for inhalation safety testing. Our focus is supporting companies and researchers to understand the interaction and safety implications of inhaled products with immune cells in the airways. Historically, alveolar safety has relied on epithelial cell models, which, though convenient, offer a narrow scope. Such limited endpoints may overlook potential long-term adverse effects on lung health, especially concerning inflammation from chronic product administration. Our services, products and experts enable our clients to understand, in detail how alveolar macrophages respond to inhaled chemicals/particulates and support classification of the response as being adaptive or adverse. We carry out a wide variety of in vitro services in-house, with a specialisation in alveolar cell painting assays. Our morph_ONE™ assay combines detailed cell morphology with cell health and biochemical readouts to help classify the mechanism of ‘foamy’, highly vacuolated macrophages to support safety assessment. Our two novel products – ImmuPHAGE™ and ImmuLUNG™ – provide in-depth analysis of macrophage responses in the lungs and epithelial tissue of the alveoli.

• Immunology/inflammation
• Eye Health
• Respiratory System
• Biomarkers