Biological processes are shaped by changes across multiple molecular layers, including RNA and proteins, with no single layer telling the whole story. Integrating complementary modalities can provide a more complete view of health and disease, revealing cellular relationships and biological mechanisms that may be missed when analyzing individual data layers alone. This webinar explores how spatial proteomics can be integrated with spatial transcriptomics on the same tissue section to maximize biological insights from valuable tissue samples.
The featured speakers will examine a workflow combining a 93-plex spatial proteomics antibody panel with spatial transcriptomics on the same tumor tissue section, highlighting practical considerations, image co-registration and opportunities for deeper tissue characterization.
This webinar will also explore research on checkpoint inhibitor-induced liver injury (ChILI), using single-cell spatial proteomics, spatial transcriptomics and bulk T-cell receptor sequencing to identify expanded cytotoxic CD8+ T-cell clones shared between liver and tumor and their interactions with macrophages.
Together, these examples demonstrate how integrating spatial protein and RNA information can reveal cellular interactions, disease mechanisms and functional biology that may not be apparent from either modality alone. Attendees will gain practical insights into multimodal spatial workflows and approaches for extracting more information from each tissue section.
Register for this webinar to learn how spatial transcriptomics can be integrated with spatial proteomics to deepen tissue characterization and biological interpretation.
Who Should Attend
This webinar will appeal to:
Clinical Development leaders
Translational Medicine Scientists
Biomarker Strategy teams
Clinical Operations professionals
Precision Medicine and Companion Diagnostic teams
Medical Directors
Clinical Laboratory Scientists
Neuroscience Drug Development teams
Oncology Translational Research teams
Pharmaceutical and Biotechnology Program leaders
CRO Scientific leadership
Clinical Biomarker Directors
What You Will Learn
Attendees will gain insight into:
How spatial proteomics and transcriptomics can be integrated on the same tissue section
Key considerations for designing a multimodal spatial workflow
How protein and RNA measurements can complement one another to deepen biological interpretation
Register free on Xtalks:
https://xtalks.com/webinars/maximize-tissue-insights-with-spatial-transcriptomics-and-proteomics/
