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Bioprocess Scientist/ Engineer

eXmoor

Bristol

eXmoor helps clients with their manufacturing of cell and gene therapies (CGT) and biopharmaceuticals. We provide; (1) translation consultancy to close the gap between R&D and clinical manufacture, (2) process development services from our wet lab in Bristol and (3) capital project design through to licensing. We have well-funded plans to expand in all areas and to add licensed GMP manufacturing for early phase clinical trials.

We are looking for bioprocess scientists or engineers to work in our upstream, downstream or analytical lab based teams to assist with the process development of Client’s therapies. This is an exciting opportunity to work with eXmoor’s globally recognised team of scientists, consultants and engineers, on a wide range of Client projects in a rapidly growing market. 

Job description: 

  • You will be developing robust, closed and scalable GMP compliant manufacturing processes for
    our clients’ CGT and biopharmaceuticals.
  • This is a generic Job Description for upstream, downstream and analytical Bioprocess Scientists /
    Engineers at various levels of seniority.

Main areas of responsibility/key duties:

  • Design, execution and delivery of CGT and biopharma process development projects which meet our client's business objectives.
  • Draw from literature and scientific knowledge to refine study objectives and protocols.
  • Assure effective technology transfer from and to clients.
  • Upstream: Carry out small scale mammalian culture experiments to assist with the development of GMP manufacturing processes at scale.
  • or, Downstream; Carry out small scale filtration and chromatography experiments to assist with the
  • or, Analytics; Perform analytical tests to support ongoing process development studies. Assays include cell counting, metabolite analysis, qPCR, ELISA, BCA, PicoGreen.
  • development of GMP manufacturing processes at scale
  • Assays include cell counting, metabolite analysis, qPCR, ELISA, BCA, PicoGreen.
  • Write protocols, analyse data, write and present reports.
  • Prepare culture media, buffers and reagents.
  • Order/maintain consumable stocks, undertake general lab housekeeping, place Purchase Orders, coordinate logistics.
  • Comply with lab documentation including Risk assessments, SOPs, COSHH forms, lab notebooks and records.
  • Comply with eXmoor QMS and H&S policy.
  • Represent eXmoor pharma externally to the broader community.