Metis Clinical is a consultancy supporting the drug development process with particular expertise in rare, paediatric diseases and niche technologies. Metis is focused on increasing client asset value at all stages of the development pathway from translational research to registration. In addition to robust non-clinical and clinical programme creation, supporting strategies may include accelerated protocol design, novel outcome measure development, disease characterisation, advisory boards, external publication opportunities and managed access programmes. Detailed knowledge and hands on experience of implementation, stakeholder engagement and creative thinking underpin the Metis approach for high impact results. www.metisclinical.eu.